PHARMACY MCQ AND NPC EXAM DAILY SERIES 7

 NPC EXAM DAILY SERIES

PHARMACY MCQ AND NPC EXAM DAILY SERIES

1. The structural feature common fro propranolol, atenolol, pindolol, metopropol in the side chain is

(A) Isopropylamino propan-2-ol 

(B) Dimethylamino propan-2-ol

(C) Diethylamino propan-2-ol 

(D) Dibutylamino propan-2-ol

2. When N-methyl group of morphine is replaced with an allyl group, the compound formed is

(A) Naloxone-morphine antagonist

(B) Natrexone-morphine agonist

(C) Nalorphine-morphine antagonist

(D) Nalbuphine-morphine agonist/antagonist

3. Nitrazepam can be synthesized from

(A) 2-Bromo-5-amino benzophenone 

(B) 2-Nitro-2-chloro acetophenone

(C) 2-Amino-5-nitro cyclohexanone 

(D) 2-Amino-5-nitro benzophenone

4. Clavulanic acid has a beta lactam ring fused to

(A) Thienyl system 

(B) Thiadiazole system

(C) Thiazolidine system 

(D) Oxazolidine system

5. A drug which has antipyretic, anti-inflammatroy and antiplatelet activity is

(A) Sulfinpyrazone 

(B) Aspirin

(C) Ticlopidine 

(D) Acetaminophen

6. Wild cherry bark contains prunasin which is a

(A) Phenolic glycoside 

(B) Isothiocyanate glycoside

(C) Coumarin glycoside 

(D) Cyanogenetic glycoside 

7. Ephedra sinica and Ephedra equisetina can be distinguished by type of

(A) Branching 

(B) Stomata 

(C) Scaly leaves 

(D) Alkaloids

8. Microprapagation of the plants is carried out through

(A) Cross fertilization 

(B) Seed germination

(C) Plant tissue culture 

(D) Grafting

9. Acontitine belongs to the group of

(A) Steroidal alkaloids 

(B) Terpenoidal alkaloids

(C) Indole alkaloids 

(D) Quinoline alkaloids

10. Crude fiber value of a drug is a measure of

(A) Soft tissue matter 

(B) Woody matter

(C) Mineral matter 

(D) Organic matter

11. One of the units used for expressing pressure is ”torr‘ and it is equal to

(A) cm of Hg 

(B) mm of Hg 

(C) psi 

(D) gauss

12. Removal of a single electron from a molecule results in the formation of

(A) Fragment ion 

(B) Metastable ion

(C) Molecular ion 

(D) Rearrangement ion

13. Nuclear magnetic moment is NOT shown by

(A)13 C 

(B) 16O 

(C) 1H 

(D)15N

14. Derivatisation techniques in HPLC are intended to enhance

(A) Molecular weight 

(B) Detectability

(C) Reversibility 

(D) Reproducibility

15. A conductance cell is calibrated by using a solution of known conductivity, i.e., usually a solution of

(A) NaCl 

(B) HgCl 

(C) KCl 

1. What is the common structural feature in propranolol, atenolol, pindolol, and metoprolol?

These beta-blockers share Isopropylamino propan-2-ol as the common side chain structure.

2. What happens when the N-methyl group of morphine is replaced with an allyl group?

This modification produces Nalorphine, which is a morphine antagonist.

3. How can Nitrazepam be synthesized?

Nitrazepam can be synthesized from 2-Amino-5-nitro benzophenone.

4. What is the fused ring system in Clavulanic acid?

Clavulanic acid has a beta-lactam ring fused to a thiazolidine system.

5. Which drug has antipyretic, anti-inflammatory, and antiplatelet effects?

Aspirin is well known for all three effects.

6. What type of glycoside is prunasin found in Wild Cherry Bark?

Prunasin is a Cyanogenetic glycoside, which releases hydrogen cyanide (HCN) upon hydrolysis.

7. How can Ephedra sinica and Ephedra equisetina be differentiated?

They can be distinguished based on their alkaloid composition.

8. What is Micropropagation, and how is it carried out?

Micropropagation is the rapid multiplication of plants through tissue culture techniques.

9. To which group does Aconitine belong?

Aconitine is a Terpenoidal alkaloid known for its neurotoxic effects.

10. What does the crude fiber value of a drug measure?

Crude fiber value measures the woody matter present in a plant material.

11. What is the unit "Torr" used for, and what does it represent?

Torr is a unit of pressure, equivalent to 1 mmHg (millimeter of mercury).

12. What happens when a single electron is removed from a molecule?

The molecule forms a molecular ion (M⁺), which is used in mass spectrometry for molecular weight determination.

13. Which nucleus does NOT show a nuclear magnetic moment?

16O (Oxygen-16) does not show a nuclear magnetic moment as it has a zero spin quantum number.

14. What is the purpose of derivatization techniques in HPLC?

Derivatization in HPLC is used to enhance detectability, making compounds easier to analyze.

15. What is used to calibrate a conductance cell?

A potassium chloride (KCl) solution is typically used for conductance cell calibration due to its stable conductivity properties.