NPC EXAM DAILY SERIES
IMPORTANT QUESTIONS
1. In nail polish, following polymer is used as a film-former :
(A) Nitrocellulose
(B) Polylactic acid
(C) Hydroxypropyl methylcellulose
(D) Cellulose acetate phthalate
2. Rabies vaccine (living) is prepared using:
(A) Sheep blood
(B) Mice lymph
(C) Horse plasma
(D) Fertile eggs
3. A drug (200 mg dose) administered in tablet form and as intravenous injection (50 mg dose) showed AUG of 100 and 200 microgram hr/mL, respectively. The absolute availability of the drug through oral administration is:
(A) 125%
(B) 250 %
(C) 12.5%
(D) 1.25%
4. Geriatric population should be included in the following Phase of clinical trials:
(A) Phase I
(B) Phase II
(C) Phase III
(D) Phase IV
5. Class 100 area is referred to:
(A) Manufacturing area
(B) Aseptic area
(C) Clean room
(D) Ware house
6. How many mL of a 1:500 w/v stock solution should be used to make 5 liters of 1:2000 w/v solution?
(A) 750 mL
(B) 1000 mL
(c) 1250 mL
(D) 1500 mL
7. The Volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL instantaneous concentration in plasma shall be:
(A)10 L
(B) 100 L
(C) 1.0 L
(D) 0.10 L
8. It is required to maintain a therapeutic concentration of 10 microgram/mL for 12 hours of a drug having half life of 1.386 hr and Vd of 5 L. The dose required in a sustained release product will be:
(A) 600 mg
(B) 300 mg
(C) 30 mg
(D) 60 mg
9. In which of the following techniques the sample is kept below triple point?
(A) Lyophilization
(B) Spray drying
(C) Spray congealing
(D) Centrifugation
10. Which of the following are widely used and excellent preservatives:
A. Quaternary ammonium compounds
B. Mercurial
C. Both
D. Acidic
11. Benzalkonium chloride is categorized as:
A. Acidic preservative
B. Neutral preservative
C. Mercurial preservative
D. Quaternary ammonium compounds
12. At which concentration, phenol act as preservative:
A. 0.2 – 0.5
B. 0.5 – 0.8
C. 0.05 – 0.1
D. None
13. Which of the following sugar has bitter taste:
A. Glucose
B. Sucrose
C. Saccharine
D. None
14. Which of the following is a synthetic sweetener:
A. Glucose
B. Sucrose
C. Sorbitol
D. Aspartame
15 . To increase the viscosity of liquid, which of the following agents are used:
A. PVP
B. Methyl Cellulose
C. Sodium Carboxy Methyl Cellulose
D. All the above
16. Which of the following agents are used as flavoring agents:
A. Menthol
B. Chloroform
C. Both
D. None