PHARMACEUTICAL DOSSAGE FORM MCQs:54

PHARMACEUTICAL DOSSAGE FORM MCQs

PHARMACEUTICAL DOSSAGE FORM MCQs

1. Presence of pinholes on surface of tablet is known as 

a. Picking 

b. Sticking 

c. Chipping 

d. Bridging 

2. While performing disintegration of floating tablets  

a. Glass tubes are left open  

b. Glass tubes are covered with lid  

c. Disintegration is not necessary  

d. None 

3. Apparatus I as per I.P is  

a. Basket 

b. Paddle 

c. Flow through cell 

d. Reciprocating cylinder 

4. Choose the correct criteria for Roche Fribilator  

a. Speed – 30 rpm 

b. Speed – 25 rpm 

c. Acceptance criteria – 1.5% 

d. Acceptance criteria – 1.2% 

5. Disintegration is required in  

a. uncoated tablets  

b. Solution 

c. suspension  

d. chewable tablets  

6. Which of the following provides the best definition to pharmaceutics? 1. It is study of dosage form design including manufacturing techniques  2. It is study of effects of drugs that have on body  

3. It is study of effect of body on drugs 

4. It is study of how drugs can be clinically synthesized  

  7. Disintegration time of sugar coated tablet is  

a. 1hr 

b. 2hr 

c. 10min  

d. 60 min

8. Enteric coated tablet should be kept in 0.1 N HCL for  

a. 60 minutes 

b. 120 minutes 

c. 30 minutes 

d. 160 minutes  

9. Dissolution apparatus flask is maintain at a temperature  a. 37 ± 0.5  

b. 37 ± 5  

c. 37 ± 2  

d. 37 ± 0 

10. Select the equation that gives the rate of drug dissolution from a tablet  a. Fick's law 

b. Henderson-Hasselbatch equation  

c. Noyes-Whitney equation  

d. Michelis Menton equation  

11. Other than tablet hardness which method is used to measure tablet strength  a. Thickness 

b. Assay 

c. Friability 

d. Organoleptic properties  

12. . Moist granules are dried at  

a. 80degree C 

b. 20 

c. 60 

d. 70

13. Which is incorrect statement  

a. Buccal route avoids first pass metabolism  

b. Oral route avoids first pass metabolism  

c. Parenteral avoids first pass metabolism  

d. Sublingual avoids first pass metabolism  

14. Following additive is used as super disintegrate  

a. Sodium starch glycollate 

b. Starch 

c. Bentonite 

d. None 

14 . The following should not be used in amine containing drugs  

a. Lactose 

b. Starch 

c. Anhydrous Lactose 

d. Sta – Rx 100 

16. Which polymer is widely sed in film coating  

a. HPMC 

b. Starch 

c. Syrup 

d. Acacia 

17. You are preparing a tablet dosage form and for you tablet to break down into fragments  and facilitate diffusion in which concentration starch is used 

a. 3-25% 

b. 5% 

c. 10% 

d. 1%

18. Separation of tablet in two or more distinct layers is  

a. Lamination 

b. Capping 

c. Sticking 

d. Blistering 

19. Which of the following is used in polishing of sugar coated tablets  a. Gelatin 

b. PEG 

c. Talc 

d. Paraffin wax 

20. Which of the non-enteric polymer has good solubility  

a. MC 

b. EC 

c. CAP 

d. HPMC 

21. The manufacture of tablets by direct compression entails a 

a. Wetting and drying process 

b. Dry blending and compression process 

c. Dry granulation process 

d. slugging process 

22. To ensure optimum and quick drug release, tablet formulations should contain an effective disintegrate such as 

a. corn starch 

b. pregelatinized starch 

c. cross linked starch 

d. hydrolyzed starch

23. Which one of the following drying method is commonly used in pharma industry for drying of tablet granules 

a. tunnel drying 

b. fluid bed drying 

c. microwave drying 

d. freeze drying 

24. 19. The acceptable weight loss in case of conventional tablets after friability test is about a. less than 0.5 to1% 

b. more than 0.5 to1 % 

c. less than 2 to 4% 

d. more than 2 to 4 % 

25. List if sucrose based diluents used in tablet formulation are given below except a. sugartab 

b. NU tab 

c. Di pacC 

d. solutab 

What does the presence of pinholes on a tablet surface indicate?

Pinholes on a tablet surface are referred to as chipping, which is a minor defect in the tablet coating.

How is the disintegration test performed for floating tablets?

For floating tablets, the glass tubes are covered with a lid to prevent the tablet from floating out.

What is Apparatus I as per the Indian Pharmacopoeia (IP)?

Apparatus I in dissolution testing is the Basket Method, which is used for tablets and capsules.

What are the correct criteria for the Roche Friabilator?

Speed: 25 rpm
Acceptance criteria: Less than 1.0% weight loss

For which dosage forms is a disintegration test required?

Disintegration testing is required for uncoated tablets, but not for chewable tablets, solutions, or suspensions.

What is Pharmaceutics?

Pharmaceutics is the study of dosage form design, including manufacturing techniques.

What is the disintegration time for sugar-coated tablets?

The disintegration time for sugar-coated tablets is 60 minutes.

How long should enteric-coated tablets remain in 0.1N HCl?

Enteric-coated tablets should be tested in 0.1N HCl for 120 minutes before moving to a buffer solution.

What is the temperature maintained in a dissolution test apparatus?

The temperature is maintained at 37 ± 0.5°C, which mimics body temperature.

Which equation describes the rate of drug dissolution from a tablet?

The Noyes-Whitney equation explains the rate of drug dissolution from a solid dosage form.