TABLET MCQs :55

 

TABLET MCQs 

TABLET MCQs 

1. Unequal distribution of color on tablet refers to  

a. Picking  

b. Mottling  

c. Capping 

d. Sticking 

2. Aerosil is commonly used as  

a. Glidant 

b. Lubricant  

c. Anti-adherant  

d. None  

3. The artificial sweetener which is about 500 times sweeter than sucrose and has a bitter  after taste is  

a. Mannitol 

b. Saccharin  

c. Aspartame 

d. Sorbitol  

4. Non-official tests for tablet dosage form is  

a. Hardness 

b. Weight variation  

c. Drug content 

d. Dissolution  

5. Which substance can be used as lubricant, anti-adherent and glidant  a. Talc 

b. Calcium silicate  

c. Colloidal silicon dioxide 

d. PEG

 6. HPMCP disintegrates at a pH  

 a. 6 

 b. 4 

 c. 2 

 d. 3 

 7. Explotab and Primojel are used in tablets as  

a. Disentigrating agent 

b. Binder 

c. Lubricant 

d. Colouring agent  

8. Binder that results in darkening of tablets over time 

a. Sucrose  

b. Acacia 

c. Gelatin  

d. Starch 

9. Fribilator is operated in  

a. 1000 rpm 

b. 100 rpm 

c. 50 rpm 

d. 25 rpm 

10. 6 glass tubes are used in DT, its length is  

a. 3 inches 

b. 6 inches  

c. 5inches 

d. 4 inches  

11. Weight variation as per USP for tablet weight for more than 324mg a. 7.5 mg 

b. 7.5 % 

c. 5 % 

d. 5 mg

12. Die table means  

a. The portion of head that hold upper punches  

b. The portion of head that hold lower punches  

c. The portion holding die  

d. The portion that guide the movement of punches  

13. If you observe rat holing during compression of tablet which of the following will you  use as remedy 

a. Addition of Sodium starch glycolate 

b. Addition of Colloidal silica 

c. Change flat punch  

d. Change deep concave punch  

14. . Regarding weight variation which on is true 

a. The tablets pass U.S.P test if no more than 3 tablets are outside the percentage limit b. The tablets pass U.S.P test if no more than 2 tablets are outside the percentage limit c. The tablets pass U.S.P test if no more than 1 tablets are outside the percentage limit d. The tablets pass U.S.P test if no more than 5 tablets are outside the percentage limit 15. How many tablets randomly selected for content uniformity test  

a. 10 

b. 20 

c. 5 

d. 30 

16. Frequency of cycles per minute during disintegration is  

a. 28-32  

b. 33-35 

c. 18-22 

d. 22-26

17. Match the following  

a. Capping i. Separation of tablet into 2-3 layers b. Lamination ii. Unequal distribution of color on tablet  c. Mottling iii. Separation of tops or bottom crowns of a tablet d. Sticking iv. Adherence of tablet material to die wall 18. Which of the following is responsible for sticking a. Excessive moisture  

b. Low moisture  

c. Both 

d. None  

19. Which of the following is used as mucoadhesive a. Acacia 

b. Sodium CMC 

c. Burnt sugar 

d. Saccharin 

20. Tablets placed between cheek and teeth are known as a. Buccal tablet 

b. Sublingual tablet 

c. Chewable tablet 

d. Lozenges 

21. Hydroxypropyl methylcellulose phthalate is  

a. Non-enteric film 

b. Enteric film  

c. A & B 

d. Not film former 

22. In table coating inadequate spread of coating is  

a. Orange peel effect 

b.Motling 

c.Sticking 

d. Blistering 

23.Durability of atablet to abrasion is evaluated by  

a. Disentigration 

b. Fribilator 

c. Thickness 

d. Hardness 

24. Which of the following flavor is used in formulation containing sour taste a. Wild cherry 

b. Vanilla 

c. Citrus 

d. Chocolate 

25."Aerosil" is the trade name for 

a. colloidal silica 

b. corn starch 

c. magnesium stearate 

d mineral oil

What does "mottling" refer to in tablet manufacturing?

Mottling refers to the unequal distribution of color on a tablet, leading to an inconsistent appearance.

What is the primary function of Aerosil in tablet formulation?

Aerosil, also known as colloidal silicon dioxide, is commonly used as a glidant to improve powder flow properties.

Which artificial sweetener is 500 times sweeter than sucrose and has a bitter aftertaste?

Saccharin is about 500 times sweeter than sucrose and may leave a slightly bitter aftertaste.

What are the non-official tests for tablet dosage forms?

• Hardness
• Weight variation
• Drug content
• Dissolution

Which substance acts as a lubricant, anti-adherent, and glidant?

Talc can function as a lubricant, anti-adherent, and glidant in tablet formulations.

At what pH does HPMCP disintegrate?

Hydroxypropyl methylcellulose phthalate (HPMCP) disintegrates at pH 6, making it an effective enteric coating material.

What are Explotab and Primojel used for?

Both Explotab and Primojel are superdisintegrants used to enhance tablet breakdown in the gastrointestinal tract.

Which binder can cause darkening of tablets over time?

Acacia may cause tablet darkening due to oxidation over time.

What is the operating speed of a Friabilator?

A Friabilator typically operates at 25 rpm to assess the tablet’s resistance to breakage.

What is the standard length of disintegration test tubes?

Disintegration test tubes used in USP tests have a length of 6 inches.

What is the acceptable weight variation limit for tablets over 324 mg?

For tablets weighing more than 324 mg, the allowable weight variation limit is 5% as per USP guidelines.

What does "Die Table" refer to in tablet manufacturing?

The die table is the portion of the tablet press that holds the dies and allows for the movement of punches.

What is "rat holing" in tablet compression, and how can it be fixed?

Rat holing occurs when powder does not flow properly into the die cavity. It can be resolved by:

• Adding colloidal silica to improve flow.
• Using a deep concave punch to prevent bridging.